Winter School Extracellular vesicles in health and disease (2026)

Day 1 - Monday, Dec. 14th: Basic Aspects of Extracellular Vesicles

• 9:00-9:15 AM
  Welcome, introduction to the Winter School and overview of the program of the day
  Speaker: Mounia CHAMI (IPMC, Valbonne, France)

• 9:15-9:35 AM
  General introduction to the basic aspects of Extracellular Vesicles
  Speaker: Inger LAURITZEN (IPMC, Valbonne, France)

• 9:35-10:05 AM
  Intercellular Communication Through Extracellular Vesicles: What Syndecan–Syntenin Teaches Us About Mechanisms and Therapeutic Opportunities
  Speaker: Pascale ZIMMERMANN (CRCM Marseille/KU Leuven, Belgium)
  In person

• 10:05-10:35 AM
  Large extracellular vesicles containing mitochondria (EVMs) derived from Alzheimer’s disease models harbor pathologic functional and molecular profiles and spread mitochondrial dysfunctions
  Speaker: Fanny EYSERT (IPMC, Valbonne, France)

• 10:35-11:00 AM - Coffee break

• 11:00-11:30 AM
  Functional analysis of apoptotic-exosome like vesicles induced by Fas death receptor activation: possible use of these EV as a biomarker of the immune response efficiency 
  Speaker: Laurent GAGNOUX (IBV, Nice, France)

• 11:30 AM-12:00 PM
  Bacterial EVs
  Speaker: Eric GUEDON (INRAE/l’Insitut Agroalimentaire, Rennes, Angers, France)
  In person or videoconference (to be confirmed)

• 12:00-1:00 PM
  Elucidating the biogenesis mechanisms of bacterial extracellular vesicles for the development of biotechnological applications  
  Speaker: José Manuel BORRERO DE ACUÑA (University of Seville, Spain)
  In person

• 1:00-2:00 PM - Lunch and Coffee break

• 2:00-2:20 PM
  EV Isolation techniques
  Speaker: Inger LAURITZEN (IPMC, Valbonne, France)

• 2:20-2:40 PM
  Protein analysis by mass spectrometry
  Anne-Sophie GAY & Fanny EYSERT (IPMC, Valbonne, France)

• 2:40-3:00 PM
  Flow cytometry analysis of extracellular vesicles
  Speaker: Julie CAZARETH (IPMC, Valbonne, France)

• 3:00-3:20 PM
  Electron microscopy as a tool to study extracellular vesicles
  Speaker: Sandra LACAS GERVAIS (CCMA, UniCA, Nice, France)

• 3:20-4:00 PM
  Immunogold technique and SMLM-super-resolution microscopy
  Mehdi Kabani (Neuro-Bicêtre, Paris-Saclay University, Paris, France)
  In person

• 4:00 - Open discussion

Day 2 - Tuesday, Dec. 16th: Extracellular Vesicles in Brain Physiology and Pathology

• 9:00-9:15 AM
  Overview of the program of the day
  Speaker: Inger LAURITZEN (IPMC, Valbonne, France)

• 9:15-9:45 AM
  Extracellular Vesicles as Long-Range Carriers of secreted PLA2G5 in the Cerebrospinal Fluid?
  Speaker: Agnès PETIT (IPMC, Valbonne, France)

• 9:45-10:15 AM
  Studies of the biogenesis, secretion, and toxicity of APP C-terminal fragment (APP-CTF)-enriched neuronal extracellular vesicles (NEVs) in Alzheimer’s disease (AD)
  Speaker: Anaïs BINI (IPMC, Valbonne, France) 

• 10:15-10:45 AM
  Single molecule detection of Tau seeds in extracellular vesicles from Alzheimer’s disease brains
  Speaker: Mehdi KABANI (Neuro-Bicêtre, Paris-Saclay university, Paris) 
  In person

• 10:45-11:15 AM - Coffee break

• 11:15-11:45 AM
  Microglial extracellular vesicles as drivers of paracrine senescence
  Speaker:  Maria Teresa GOLIA (University of Milano, Italy)
  Videoconference

• 11:45 AM-12:15 PM
  Non-coding RNA in extracellular vesicles
  Speaker: Tom DRIEDONLS (University Medical Center Utrecht, Netherlands)
  Videoconference

• 12:15-1:00 PM
  EVs in Alzheimer’s disease and tauopathies
  Speaker: Luc BUÉE (Lille University, Lille, France)
  In person

• 1:00-2:00 PM - Lunch and Coffee break

• 2:30-5:30 PM - Workshop  - For Université Côte d'Azur Master students only
  Coordinators: Fanny EYSERT / Anaïs BINI / Elodie DELAQUAIZE / Julie CAZARETH / Inger LAURITZEN  

Day 3 - Wednesday, Dec. 176th: Extracellular Vesicles in Cancer

• 09:00–09:15 AM
  Overview of the program of the day
  Speaker: Gérard LAMBEAU (IPMC, Valbonne, France)

• 09:15–10:00 AM
  Tumor-immune system cross-talk : different roles of soluble secreted factors and extracellular vesicles
  Speaker: Clotilde THÉRY (Curie Institute, Paris, France)
  Videoconference

• 10:00–10:30 AM
  Title to be announced
  Nícolas Jones VILLARINHO (C3M, Nice; France)

• 10:30–11:00
  From membrane remodeling to EV diversity: uncovering the role of CD133 in cancer
  Speaker: Gisela D'ANGELO (Curie Institute, Paris, France)
  In person

• 10:45-11:15 AM - Coffee break

• 11:30–12:00
  EV-mediated crosstalk in pancreatic cancer
  Speaker: Richard TOMASINI (CRCM, Marseille, France)
  In person

• 12:00–12:30
  ADAM10 shapes extracellular vesicle composition and signaling
  Speaker : Rania GHOSSOUB (CRCM, Marseille, France)
  In person

• 1:00-2:00 PM - Lunch break

• 2:30-5:30 PM - Workshop  - For Université Côte d'Azur Master students only
  Coordinators: Fanny EYSERT / Anaïs BINI / Elodie DELAQUAIZE / Julie CAZARETH / Inger LAURITZEN  

Day 4 - Thursday, Dec. 17th: Extracellular Vesicles Functions

• 09:00–09:15 AM
  Overview of the program of the day
  Speaker: Fanny EYSERT (IPMC, Valbonne, France)

• 09:15–10:00 AM
  Tracking EVs in vitro and in vivo
  Speaker: Guillaume VAN NIEL (CRCI2NA, Nantes, France)
  Videoconference

• 10:00–10:30 AM
  Tumor-derived extracellular vesicles facilitate metastasis onset
  Speaker: Vincent HYENNE (Inserm U1109, Strasbourg, France)
  Videoconference

• 10:30–11:00
  Biological properties and physiological functions of EVs
  Speaker: María YÁÑEZ-MÓ (University of Madrid, Spain)
  Videoconference

• 11:00-11:30 AM - Coffee break

• 11:30 AM–12:15 PM
  EVs in brain plasticity and recovery
  Speaker: Stefan MOMMA (Goethe University Frankfurt, Germany)
  Videoconference

• 12:15-2:00 PM - Lunch break

• 2:00-5:00 PM - Workshop  - For Université Côte d'Azur Master students only
  Coordinators: Fanny EYSERT / Anaïs BINI / Elodie DELAQUAIZE / Julie CAZARETH / Inger LAURITZEN  

Day 5 - Friday, Dec. 18th: Extracellular Vesicles as Disease Biomarkers and Therapeutic Targets

• 09:00–09:15 AM
  Overview of the program of the day
  Speaker: Mounia CHAMI (IPMC, Valbonne, France)

• 09:15–10:00 AM
  B-FHIT Bioproduction For Health and Innovative Therapy
  Speaker: Mathilde MOSSER (Nantes, France)
  Videoconference

• 10:00–10:30 AM
  MSC-EV surface engineering for biodistribution and cargo delivery
  Marie MORILLE (Montpellier University, France)
  Videoconference or in person to be confirmed)

• 10:30–11:00
  Cellular and molecular characterization of EV uptake and delivery
  Speaker: Grégory LAVIEU (Paris Cité University, NABI, Paris, France)
  In person

• 11:00-11:30 AM - Coffee break

• 11:30 AM–12:00 PM
  Investigating human Amniotic Secretome forMulations for cArdioprotective paRacrine Therapy – the AmnioSMART project
  Speaker: Sveva BOLLINI (University of Genova, Italy)
  In person

• 12:00 PM–12:30 PM
  A NanoBioAnalytical Platform for the characterization of Large EVs associated with cytotoxic stress: toward a generic tool for discovering new biomarkers?
  Speaker: Wilfrid BOIREAU (FEMTO-ST Institute, Besançon, France)
  In person

• 12:30-2:00 PM - Lunch break & group photo

• 2:00-5:00 PM
  - Concluding remarks
  - Winter school evaluation
  - Students evaluation (for Université Côte d'Azur Master students only)

PROGRAM DOWNLOAD (coming soon)

SCIENTIFIC COMMUNITY

• The Extracellular Vesicles in Health & Disease Winter School is open to any member of the international scientific community: students, post-doctoral fellows, researchers, and collaborators...

PHD STUDENTS

• PHD students have no obligation to attend the entire winter school
• They can attend from half a day to the full week
• Hours will be validated based on the seminars the students choose to attend (attendance sheet to be completed)
• PHD students must registrer via the ADUM platform:

MASTER STUDENTS

• Students from Université Côte d'Azur "Science du Vivant" Master's degree
  This Winter School is mandatory for students who chose the "Winter School UE".
  These students don't need to register via the registration form on this page since they're automatically enroled as part of their training.
• Students from Masters degrees other than "Science du Vivant"
  Students from other Masters degrees are welcome, but they must register using the general sign-up form

Organizing Committee

The strength of this Winter School lies in its people.
The Organizing Committee represents a collaboration of disciplines and perspectives, all aligned to create a week where knowledge meets opportunity :

• Mounia CHAMI - Coordinator - IPMC
• Inger LAURITZEN - Coordinator - IPMC
• Fanny EYSERT - Coordinator - IPMC
• Anaïs BINI - Coordinator - IPMC
• Elodie DELAQUAIZE - Coordinator - IPMC
• Julie CAZARETH - Coordinator - IPMC
• Guillaume CHAUDE - Communication officer - LIFE Graduate School
• Line-Aurore MARCH - Educational Engineer - LIFE Graduate School
• Gaelle YOUSSEF - Franco Indian Campus coordinator - LIFE Graduate School